Brian Federici

Project Lead

The Federici lab engineers new larvicidal bacteria active against all major genera of vector mosquitoes and black flies. We focus on recombining genes from Bacillus thuringiensis and Lysinibacillus sphaericus, engineering these for high levels of mosquitocidal protein synthesis. Current recombinants being considered for commercial development are ten-fold more potent than wild type strains in existing commercial products used against Aedes, Anopheles, and Culex mosquitoes. These recombinants have all been engineered to avoid resistance in mosquito populations.